Liesbet Temmerman

The paper identifies an autocrine feedback mechanism in C. elegans AVK neurons that regulates neuropeptide expression and secretion through FLP-1 and DMSR-7 interactions.

This study identifies 2143 flp-genes across 100+ nematode species, revealing evolutionary patterns and expression dynamics of FLPs in parasitic nematodes.

The paper identifies 31 Nematostella vectensis GPCRs activated by 14 neuropeptides, showing cnidarian and bilaterian peptidergic systems expanded independently.

The paper identifies and functionally characterizes a novel overlapping gene azyx-1 in C. elegans, showing its role in regulating zyx-1 proteoforms and affecting muscular integrity and locomotion.

This study shows royalactin extends C. elegans lifespan by increasing protein translation and proteasome activity, suggesting a new mechanism for longevity.