Nomdo M. Jansonius

Genome-wide association meta-analysis identifies novel ancestry-specific primary open-angle glaucoma loci and shared biology with vascular mechanisms and cell proliferation

This study identifies ancestry-specific and sex-specific genetic loci for primary open-angle glaucoma through a meta-analysis of 15 biobanks, highlighting shared biology with vascular mechanisms and cell proliferation.

Integrating genetic regulation and single-cell expression with GWAS prioritizes causal genes and cell types for glaucoma

Meta-analysis fine-mapping is often miscalibrated at single-variant resolution

This paper shows that meta-analysis fine-mapping is often miscalibrated due to cohort heterogeneity and introduces a QC method to identify suspicious loci.

Global Biobank Meta-analysis Initiative: powering genetic discovery across human diseases

Meta-analysis of harmonized GWAS from up to 18 biobanks (six ancestry groups) across 14 endpoints replicated 320 known loci and identified 188 apparently novel loci.

White matter alterations in glaucoma and vision-deprived brains differ outside the visual system

The paper compares white matter microstructure changes in glaucoma and monocular blindness, finding distinct patterns outside the visual system.

Visual field reconstruction using fMRI-based techniques

This study evaluates fMRI-based techniques for visual field reconstruction, finding they can detect large VF defects and provide reliable VF information comparable to standard automated perimetry.