Steve L. Bonilla

Quantifying RNA Folding Equilibria from Unclassified Cryo-EM Particle Images

This paper uses Bayesian ensemble reweighting on unclassified cryo-EM images to quantify RNA folding equilibria, showing agreement with bulk solution measurements.

RNA 3D Motif Dynamics Guide Assembly of the Replication Initiation Complex in Flaviviruses

The paper shows that dynamic RNA structures guide viral replication by enabling conformational changes necessary for protein binding and function.

An A-rich linker between dengue virus tandem xrRNAs facilitates functional coordination

This paper identifies an A-rich linker between tandem xrRNAs in DENV2 that stabilizes their structural coupling, influencing sfRNA patterns and viral fitness.

Exploring the energetic and conformational properties of the sequence space connecting naturally occurring RNA tetraloop receptor motifs

This study uses high-throughput thermodynamic measurements to explore how sequence changes affect the binding properties of RNA tetraloop receptor motifs, revealing complex sequence-fitness landscapes.