Vivian Jou

This study uses single-cell RNA sequencing to identify fibroblast subpopulations and genes linked to fibrosis and regeneration, then tests their effects using AAV gene delivery in mouse digits.

The paper shows Mest expression in mouse digit regeneration is regulated by promoter switching, not imprinting, and modulates neutrophil response.

This study uses live-cell imaging in yeast to show how PIC components explore the nucleus and assemble at promoters, revealing spatio-temporal coordination in transcription initiation.

The paper uses single-molecule imaging to study chromatin remodelers in budding yeast, revealing their fast kinetics and ATP-dependent dissociation from chromatin.

The paper uses live-cell single particle imaging to show that RNA polymerase II and Kin28/Cdk7 kinase are required for H2A.Z eviction in yeast, linking it to transcription processes.