Ino D. Karemaker

This study introduces QuPID-MS to measure protein phase separation in cells, showing weak interactions drive proteome demixing and influence environmental response.

This paper optimizes diagonal-PASEF mass spectrometry with retention time down-sampling, improving identifications and quantification in proteomics.

This study identifies a stress response pathway linking nucleolar disruption to cellular quiescence and secretion, revealing its role in cancer progression.

The paper identifies a regulatory variant driving microphthalmia by analyzing its effects in mouse models and linking it to FOXE3 expression and ocular development.

This study investigates the roles of MBD2 and MBD3 isoforms in NuRD complex function during differentiation, showing that MBD2b can fully rescue MBD3 loss while MBD2t cannot.

The paper identifies sequence preferences for de novo DNA methylation by DNMT3A and DNMT3B in mouse stem cells, showing structural basis for context-specific methylation.