Author

Yingchun Xu

Chinese Academy of Medical Sciences & Peking Union Medical CollegeORCID 0000-0002-6534-9647Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Bo ZhengiD· 1 shared Bo ZhuiD· 1 shared Chong Li· 1 shared Chun‐Wei PengiD· 1 shared Cui Hua LiuiD· 1 shared David S. PerliniD· 1 shared Feiyi LiuiD· 1 shared Guohui Shi· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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1 shared paperMicrobiology

Bo ZhengORCID

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3 papers

Recent·Most cited

The common evolution of fungicide persistence in cryptococcosis patients

Yuyan Xie, Weixin Ke, Xin Fan, Heping Xu, Wenzhao Wang, Zhen Zeng, Na Zhang, Haoran Ma, Zhongjie Tang, Huawei Zhu, Lei Jiang, Bo Zhu, Guohui Shi, Sihan Yang, Minling Yu, , Linqi Wang

The paper identifies common evolutionary events leading to fungicide persistence in Cryptococcus neoformans clinical isolates and shows ACO2 deficiency as a key predictor of high persistence.

bioRxiv · Aug 26, 2026 · PreprintMicrobiology

Pre-existing antibiotic tolerance facilitates plasmid-mediated carbapenem resistance evolution in clinical Klebsiella pneumoniae

Weili Zhang, Bo Zheng, Menglan Zhou, Rong Zhang, Yingchun Xu, Jiafeng Liu

This study shows pre-existing antibiotic tolerance in K. pneumoniae isolates facilitates plasmid-mediated carbapenem resistance evolution.

bioRxiv · Aug 24, 2026 · PreprintMicrobiology

Selective Chemical Labeling and Sequencing of 5-Hydroxymethylcytosine in DNA at Single-Base Resolution

Xiaogang Li, Xinxin Shi, Yin Gong, Wenting Guo, Yuanrui Liu, Chun‐Wei Peng, Yingchun Xu

The paper develops a method to enrich and sequence 5-hydroxymethylcytosine (5hmC) at single-base resolution using chemical labeling and enzyme-based deamination.

Frontiers in Genetics · Nov 17, 2021Peer-reviewedGenomics