Author
Chinese Academy of Medical Sciences & Peking Union Medical CollegeORCID 0000-0003-3585-7728Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Xiaogang Li, Xinxin Shi, Yin Gong…·Yingchun Xu
The paper develops a method to enrich and sequence 5-hydroxymethylcytosine (5hmC) at single-base resolution using chemical labeling and enzyme-based deamination.
Laura Fumagalli, Florence L. Young, Steven Boeynaems…·Philip Van Damme
This study shows that C9orf72 repeat expansions produce toxic arginine-rich DPRs that disrupt axonal transport by interacting with microtubules and motor proteins, contributing to ALS/FTD.
Wenting Guo, Shaohua Wang, Xiaoshan Zhang…·Yangming Wang
This study shows that an acidic microenvironment, caused by lactate accumulation, promotes pluripotency in mouse and human ESCs through multiple mechanisms involving histone modification, mRNA stability, and microRNA regulation.