Synthetic BiologyApplied and Environmental MicrobiologyPeer-reviewed
Awakening prime editing for precision engineering of probiotic Escherichia coli Nissle 1917
Pei-Ru Chen, Ying Wei, Xin Li…·Peng‐Fei Xia
This paper develops a streamlined prime editing system for Escherichia coli Nissle 1917, achieving high editing efficiencies and reduced off-target effects for DNA deletion, insertion, and substitution.
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