Julian A. Hiscox

This study investigates the phenotypic effects of naturally occurring MERS-CoV Spike mutations on virus entry and neutralisation, identifying mutations that enhance entry or confer resistance to neutralisation.

This study shows Amphotericin B and Nystatin enhance SARS-CoV-2 replication in vitro by promoting viral entry, suggesting they should not be used in active COVID-19 cases.

This study examines how molnupiravir and nirmatrelvir affect SARS-CoV-2 genome diversity in immunocompromised mice, finding reduced viral load and specific mutations but no major consensus sequence changes.

The paper develops an amplicon-based sequencing method for rapid MERS-CoV genotyping and evaluates it alongside metagenomic analysis to study the microbiome in MERS patients.

The paper compares immune responses in influenza and SARS-CoV-2 infected patients and COVID-19 survivors using transcriptomic data, identifying distinct immune signatures and prognostic indicators.