Author

Svenja Möller

University Medical Center Hamburg-EppendorfORCID 0000-0002-6607-426XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Aymelt ItzeniD· 2 shared Alexander BaumgartiD· 1 shared Andrea MagniiD· 1 shared Bente SiebelsiD· 1 shared Don C. LambiD· 1 shared Ecenaz BilgeniD· 1 shared Giorgio Bonollo· 1 shared Giorgio ColomboiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Aymelt ItzenORCID

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2 papers

Recent·Most cited

BiochemistryFEBS LettersPeer-reviewedSep 18, 2026

The Shewanella oneidensis Fic enzyme SoFic targets the switch-Iregion of EF-Tu for AMPylation

Svenja Möller, Vivian Pogenberg, Alexander Baumgart…·Aymelt Itzen

This study identifies EF-Tu as a target of the Fic enzyme SoFic, showing AMPylation disrupts EF-Tu's switch-I region and inhibits translation, while SoFic also binds DNA, suggesting dual regulatory roles.

DOI 10.1002/1873-3468.70457

bacteria (other)proteomics

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BiophysicsProceedings of the National Academy of SciencesPeer-reviewedAug 21, 2025

Resolving the Dynamic Interplay of the Conformational States in the TPR Domain of Human AMPylase FicD

Svenja Runge, Ecenaz Bilgen, Andrea Magni…·Don C. Lamb

This study uses smFRET to analyze conformational dynamics of FicD's TPR motifs, showing equilibrium between TPR-in and TPR-out states influenced by ATP and BiP.

2 citations

humanfluorescence / live-cell microscopy

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