ImmunologybioRxivPreprint
Therapeutic ICOS blockade reduces T follicular helper cells and improves allergic airway disease
F. I. Uwadiae, C.J. Pyle, S.A. Walker…·J.A. Harker
This study shows that blocking ICOS reduces T follicular helper cells and alleviates allergic airway disease in mice by impairing germinal center responses and reducing allergen-specific IgE.
DOI 10.1101/250217