Author

C.J. Pyle

ORCID 0000-0002-1408-1134Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

C.M. LloydiD· 1 shared F. I. UwadiaeiD· 1 shared J.A. HarkeriD· 1 shared John S. TregoningiD· 1 shared Michael R. EdwardsiD· 1 shared Neeta D Patel· 1 shared Patricia Londoño-Hayes· 1 shared Paul HambliniD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

C.M. LloydORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJan 7, 2026

A rhinovirus vaccine evokes T cell mediated cross-reactive immunity in a preclinical model of rhinovirus infection

Stephen Michael Shaw, Chloe Julia Pyle, Neeta D Patel…·Sebastian Lennox Johnston

This study evaluates a rhinovirus (RV) vaccine, showing it induces cross-reactive T cell immunity and protection against heterotypic RV infection in mice.

1 citation

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintJan 18, 2018

Therapeutic ICOS blockade reduces T follicular helper cells and improves allergic airway disease

F. I. Uwadiae, C.J. Pyle, S.A. Walker…·J.A. Harker

This study shows that blocking ICOS reduces T follicular helper cells and alleviates allergic airway disease in mice by impairing germinal center responses and reducing allergen-specific IgE.

DOI 10.1101/250217

mousebulk RNA-seq

𝕏 PostBluesky