Daniel Cazares

Competition constrains parasite adaptation to thermal heterogeneity

This study shows that competition reduces thermal adaptation in bacteriophages under fluctuating temperatures compared to monoculture conditions.

Trade-offs between phage resistance and conjugative ability shape the ecological and evolutionary response of a multidrug resistance plasmid to plasmid-dependent phage

This study shows that multidrug resistance plasmids face a trade-off between phage resistance and conjugative ability, which affects their evolutionary response to plasmid-dependent phages.

Evolutionary rescue accelerates competitive exclusion in a parasite community

This study shows evolutionary rescue prevents parasite extinction but can destabilize communities by promoting competitive exclusion in a viral parasite system under thermal stress.

Plasmids link antibiotic resistance genes and phage defense systems in E. coli

The paper analyzes 2,559 E. coli plasmids to show that antibiotic resistance genes and phage defense systems are physically linked, suggesting potential interactions between antibiotic use and phage therapy.

Pre and Post antibiotic epoch: insights into the historical spread of antimicrobial resistance

The paper compares plasmids from pre-antibiotic era bacteria with modern plasmids to show how resistance genes evolved and spread over time.