LIMD1 Loss Confers a GPX4-Dependent Cell State in Lung Cancer
Akash Saha, Paul Grevitt, Jair Marques Junior, Alex von Kriegsheim, Kunal Shah, Zhen Gao, Brent R. Stockwell, Andrew J. Finch, Barrie Peck, Tyson V. Sharp
This study identifies GPX4 as a therapeutic target in LIMD1-deficient lung cancer by showing its role in ferroptosis susceptibility.
bioRxiv · Jun 6, 2025 · PreprintCancer Biology