The paper presents CattleGTEx, a resource characterizing regulatory effects in cattle, resolving GWAS signals and providing insights into adaptive evolution and selection.

bioRxiv · Mar 21, 2026 · PreprintGenetics

Genomic evaluation of circulating proteins for drug target characterisation and precision medicine

Lasse Folkersen, Stefan Gustafsson, Qin Wang, Daniel Hvidberg Hansen, Åsa K. Hedman, Andrew Joseph Schork, Karen M. Page, Daria V. Zhernakova, Yang Wu, James E. Peters, Niclas Ericsson, Sarah E. Bergen, Thibaud Boutin, Andrew D. Bretherick, Stefan Enroth, , Anders Mälarstig

The paper identifies pQTLs for cardiovascular proteins and uses them to evaluate drug targets and suggest new candidates for precision medicine.

bioRxiv · Apr 3, 2020 · PreprintGenetics

Whole-exome sequencing identified rare variants associated with body length and girth in cattle

Yan Chen, ‬Min Du, Yining Liu, Xue Gao, Wengang Zhang, Ling Xu, Lupei Zhang, Huijiang Gao, Lingyang Xu, Bo Zhu, Min Zhao, Junya Li

The paper identifies rare variants associated with body length and girth in cattle through whole-exome sequencing and functional analysis.

bioRxiv · Mar 23, 2018 · PreprintGenetics

Improving the Efficiency of Genomic Selection in Chinese Simmental beef cattle

Jiangwei Xia, Yang Wu, Huizhong Fang, Wengang Zhang, Yuxin Song, Lupei Zhang, Xue Gao, Yan Chen, Junya Li, Huijiang Gao

This study improves genomic selection efficiency in Chinese Simmental beef cattle by optimizing kinship matrix estimation using SNP data and feature selection in GBLUP.

bioRxiv · Jul 17, 2015 · PreprintGenomics