Author

Ralf L. J. Schmidt

Gladstone InstitutesORCID 0000-0002-6697-0363Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Alexander MarsoniD· 2 shared Alexis TalbotiD· 1 shared Allison Grace RothrockiD· 1 shared Angela ToiD· 1 shared Avishai ShemeshiD· 1 shared Byungjin HwangiD· 1 shared Carl C. WardiD· 1 shared Chang LiuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersGenomics

Alexander MarsonORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintAug 11, 2026

A genome-wide CRISPR activation map of surface protein expression in human CD4 T cells

Yutong V Wang, Junha Park, Min Cheol Kim…·Byungjin Hwang

This paper introduces SCITO-Perturb-seq, a CRISPRa platform that maps surface protein regulation in CD4 T cells, finding 16% of activated genes alter surface protein expression.

DOI 10.64898/2026.08.08.743670

humanCRISPR screen

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ImmunologybioRxivPreprintOct 5, 2025

Site-specific genome engineering of primary human natural killer cells for programmable anti-tumor function

Vincent Allain, Allison Grace Rothrock, Pierre-Louis Bernard…·Justin Eyquem

This paper develops a genome engineering workflow for primary human NK cells using CRISPR/Cas9 and AAV6 to integrate and disrupt genes, enhancing anti-tumor function through targeted CAR expression.

DOI 10.1101/2025.10.05.680386

humangenetic perturbation / CRISPR

𝕏 PostBluesky