Author

Julian R. Smith

University of WashingtonORCID 0000-0002-8167-4335Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Assay:proteomics· 1

Frequent Co-Authors

Daphne C. AvgoustiiD· 2 shared Edward A. ArnoldiD· 2 shared Laurel E. Kelnhofer-MillevolteiD· 2 shared Adam P. GeballeiD· 1 shared Cole M. Pugliano· 1 shared Daniel H NguyeniD· 1 shared Daniel H. Nguyen· 1 shared Eui Tae KimiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Daphne C. AvgoustiORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Human cytomegalovirus induces neuronal gene expression for viral maturation

Laurel E. Kelnhofer-Millevolte, Julian R. Smith, Daniel H Nguyen, Lea S Wilson, Hannah C Lewis, Edward A. Arnold, Mia R. Brinkley, Kihye Shin, Jin‐Hyun Ahn, Eui Tae Kim, Katarzyna Kulej, Adam P. Geballe, Srinivas Ramachandran, Daphne C. Avgousti

This study shows that HCMV uses macroH2A1 to reorganize host cell structures and induce neuronal gene expression, which is critical for viral maturation.

Nature Communications · Aug 8, 2025Peer-reviewedMicrobiology

CELF2 suppresses endogenous RNA ligands that activate RIG-I-mediated interferon induction

Julian R. Smith, Olivia C. Kern, Gargi Mishra, Nandan S. Gokhale, Noa Etzyon, Kim Y. Somfleth, Johannes Schwerk, Kenji Nakamichi, Cole M. Pugliano, Zachary Lindbloom-Brown, Michael Gale, Ram Savan

bioRxiv · Mar 27, 2025 · PreprintImmunology

Post-translational modifications on protein VII are important during the early stages of adenovirus infection.

Edward A. Arnold, Julian R. Smith, Katie Leung, Daniel H. Nguyen, Laurel E. Kelnhofer-Millevolte, Monica S. Guo, Jason G. Smith, Daphne C. Avgousti

This study investigates how post-translational modifications on adenovirus protein VII affect its function during early and late infection stages, revealing their role in localization, transcription, and protein interactions.

Journal of Virology · Dec 31, 2024Peer-reviewedMicrobiology