Author

Jaffarguriqbal Singh

Yale UniversityORCID 0000-0002-6730-0222Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Cassandra Santaella BishopiD· 1 shared Christian Felipe RuiziD· 1 shared Mandar Deepak MuzumdariD· 1 shared Moitrayee BhattacharyyaiD· 1 shared Wenxue LiiD· 1 shared Xiangyu GeiD· 1 shared Yansheng LiuiD· 1 shared

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7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Cassandra Santaella BishopORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintJun 20, 2025

Phosphoinositide 3-kinase regulates wild-type RAS signaling to confer resistance to KRAS inhibition

Xiangyu Ge, Jaffarguriqbal Singh, Wenxue Li…·Mandar Deepak Muzumdar

This study shows PI3K promotes resistance to KRAS inhibition in PDAC by activating wild-type RAS signaling through GAB1 recruitment and MAPK activation.

1 citation

humanproteomics

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