Sebald A. N. Verkuijl

The paper outlines a target product profile for a rapid diagnostic test to detect gene drive mosquitoes in the field, focusing on usability, sensitivity, and compatibility with pooled testing.

Across nearly one million progeny from 10 species, species best predicts homing drive inheritance, while promoter, parent sex and maternal deposition each explain little of the inheritance variation.

This study develops and characterizes a nanosd integral gene drive in Anopheles gambiae, achieving high gene drive rates and showing potential for malaria vector control.

This study investigates inheritance bias mechanisms in a CRISPR gene drive in Aedes aegypti, finding two distinct mechanisms: homing in double heterozygous males and meiotic drive.