Mauro Petrillo

Evo 2 as a classification machine: evidence from in-context learning and mechanistic interpretability

This paper evaluates Evo 2's in-context learning capabilities on genomic sequences, finding strong performance on short sequences but degradation with length, and no benefit from model scaling.

Evo 2's Perception of Single Nucleotide Substitutions in the Genes of Two Plant Model Organisms

Evo 2 7B assigns higher perplexity to plant gene alleles carrying randomly simulated single-nucleotide substitutions than to those observed in vivo, in Arabidopsis and rice; significant but small effect.

In Silico Analysis Of The Effects Of Omicron Spike Amino Acid Changes On The Interactions With Human ACE2 Receptor And Structurally Characterized Complexes With Human Antibodies

The paper analyzes how Omicron's spike mutations affect interactions with ACE2 and antibodies using 3D structures, predicting increased transmissibility and mixed antibody effects.

Expanding the Galaxy's reference data

The paper describes integrating refgenie into Galaxy to manage and share reference datasets, with tools for retrieval and a global repository for easy access.