Author

Sergio Villazala‐Merino

Centre National de la Recherche ScientifiqueORCID 0000-0002-6791-3272Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Adriana GruppiiD· 1 shared Andrew S. MacDonaldiD· 1 shared Carolyn G. KingiD· 1 shared Claude GrégoireiD· 1 shared Judith E. AlleniD· 1 shared Laura AlmadaiD· 1 shared Lucas BertoiaiD· 1 shared Mara EspositoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Adriana GruppiORCID

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1 paper

Recent·Most cited

Access to germinal center IL-4 microniches drives tissue-divergence of IgE memoryresponses

Sergio Villazala‐Merino, Lucas Bertoia, Romain Fenouil, Myriam Moussa, Samuel Origlio, Claude Grégoire, Laura Almada, Mara Esposito, Stefano A. P. Colombo, Adriana Gruppi, Judith E. Allen, Andrew S. MacDonald, Nicolas Fazilleau, Carolyn G. King, Mauro Gaya

The paper shows that IgE memory responses are confined to lymphoid organs through GC IL-4 microniches, which are critical for IgE production during allergen recall.

bioRxiv · Dec 5, 2025 · PreprintImmunology