Adriana Gruppi

Distinct profiles and antibody production by splenic and lymph node antibody-secreting cells in Trypanosoma cruzi infection

The paper compares splenic and lymph node antibody-secreting cells in Trypanosoma cruzi infection, finding distinct transcriptional, phenotypic, and functional profiles.

Dual Th1 and tissue-repair Treg cells accumulate in skeletal muscle preserving tissue integrity during infection

The paper identifies tissue-adapted Treg cells in skeletal muscle during chronic parasitic infection that balance inflammation and tissue repair.

Tissue-distinct Features of Follicular Cytotoxic CD8+ T Cells in Trypanosoma cruzi infection

This study identifies tissue-specific features of T follicular cytotoxic cells in T. cruzi infection, showing distinct metabolic and functional states in spleen and lymph nodes.

A mouse model to study Rio Negro virus pathogenesis: a neglected member of the Venezuelan equine encephalitis virus complex

This study develops a lethal mouse model to study Rio Negro virus pathogenesis, revealing systemic and neurological effects, immune system disruption, and neuroinflammation.

Access to germinal center IL-4 microniches drives tissue-divergence of IgE memoryresponses

The paper shows that IgE memory responses are confined to lymphoid organs through GC IL-4 microniches, which are critical for IgE production during allergen recall.