Mauro Gaya

This study generates a transcriptomic atlas of in vitro-derived mononuclear phagocytes to clarify the identity of moDCs and their in vivo counterparts.

The paper shows that IgE memory responses are confined to lymphoid organs through GC IL-4 microniches, which are critical for IgE production during allergen recall.

This study shows that plasmacytoid dendritic cells (pDCs) and their interferons are dispensable or harmful in systemic and respiratory viral infections in mice.

The paper shows that mucosal B cell memory selection diverges between lungs and gut, favoring MBCs and PCs respectively, driven by tissue-specific BCR isotype usage rather than affinity.

The paper tracks GC-derived B cells in lymph nodes to identify PrePC cells and their transition to plasma cells, revealing spatial and transcriptional changes during differentiation.