Daniel Kerschensteiner

This study develops a biocompatible clearing agent for live mouse brain tissue, enabling deeper optical imaging with reduced laser intensity.

The paper identifies neuroprotective genes in RP using CRISPR screens in mice and human retinal models, showing that UFD1 and UXT overexpression preserves photoreceptors and function.

This study evaluates two CRX augmentation strategies in mouse models of CRX-associated CoRDs, showing improved cone and rod survival and function.

The paper investigates the subcellular pathways of VG3 amacrine cells in the mouse retina, revealing their role in transmitting object-motion-selective signals through interactions with bipolar cells and RGCs.

This paper identifies a unique retinal ganglion cell type, tSbC RGCs, and maps their precise axon projections to specific brain regions with developmental precision.

The paper shows that VGluT3-expressing amacrine cell neurites process visual information locally, responding to local motion but not global motion.