Author

Lawrence W. Dobrucki

University of Illinois Urbana-ChampaignORCID 0000-0002-6807-217XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam LenczowskiiD· 1 shared Alvaro Gonzalo HernandeziD· 1 shared Anasuya Das GuptaiD· 1 shared Auinash KalsotraiD· 1 shared Catherine C. ApplegateiD· 1 shared Chaitali MisraiD· 1 shared Claire P. SchaneiD· 1 shared Darren J. ParkeriD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCancer Biology

Adam LenczowskiORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintFeb 16, 2026

The Role of the Receptor for Advanced Glycation End-Products in Cancer: Evidence from a Systematic Review and Meta-Analysis

Michael B. Nelappana, Paweł Wityk, Catherine C. Applegate…·Lawrence W. Dobrucki

This study conducts a systematic review and meta-analysis to assess the role of RAGE in cancer, finding it correlates with cancer progression and poor patient survival.

1 citation

statistical model

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Cancer BiologyCancer LettersPeer-reviewedOct 29, 2025

Neutrophils exposed to a cholesterol metabolite secrete extracellular vesicles that promote epithelial-mesenchymal transition and stemness in breast cancer cells.

Natalia Krawczyńska, Yu Wang, Ki Lim…·Erik Russell Nelson

This study shows that 27HC-treated neutrophils release sEVs that induce EMT and stemness in breast cancer cells via WNT/β-catenin pathway activation.

14 citations

humanbulk RNA-seq

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GeneticsDevelopmental CellPeer-reviewedFeb 27, 2020

Overexpression of a non-muscle RBFOX2 isoform triggers cardiac conduction defects in myotonic dystrophy

Chaitali Misra, Sushant Bangru, Feikai Lin…·Auinash Kalsotra

This study identifies overexpression of a non-muscle RBFOX2 isoform as a cause of cardiac conduction defects in myotonic dystrophy by inducing arrhythmia and altering ion channel splicing.

45 citations

mousebulk RNA-seq

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