Noboru Hiroi

Tbx1 Heterozygosity in the Oligodendrocyte Lineage Shifts Myelinated Axon Composition in the Mouse Fimbria Without Behavioral Impairments

This study shows that Tbx1 heterozygosity in the oligodendrocyte lineage causes a shift in myelinated axon composition in the mouse fimbria but not behavioral impairments.

Neonatal social communication and single genes predict the variability of post-pubertal social behavior in a mouse model of paternal 15q11-13 duplication

The paper predicts post-pubertal social behavior variability in a mouse model of paternal 15q11-13 duplication using neonatal social communication and gene expression data.

Structural alterations in the amygdala and impaired social incentive learning in a mouse model of a genetic variant associated with neurodevelopmental disorders

This study examines structural brain changes and social behavior in Tbx1 heterozygous mice, linking reduced amygdala volume to impaired social incentive learning.

Advanced paternal age diversifies individual trajectories of vocalization patterns in neonatal mice

Advanced paternal age affects vocal development in early postnatal mice, with more pups showing atypical developmental trajectories.

Transcriptional regulation of neonatal neural stem cells is a determinant of social behavior

The paper investigates how Tbx1 deficiency in neonatal neural stem cells affects social behavior and identifies its role in neurodevelopmental disorders.

Tbx1, a 22q11.2-encoded gene, is a link between alterations in fimbria myelination and cognitive speed in mice

This study shows that Tbx1 deletion in mice affects myelination and cognitive speed, linking 22q11.2 CNV alterations to cognitive deficits.

Maternal approach behaviors toward neonatal calls are impaired by mother's experiences of raising pups with a risk gene variant for autism

The paper shows that maternal approach behaviors toward neonatal mouse calls are influenced by the mother's prior experience with pups carrying a risk gene variant for autism.