Yilin Chen

This study demonstrates that structure-based mutagenesis of CspZ-YA improves antigen stability and immunogenicity, supporting its use in Lyme disease vaccine design.

This paper describes the development of a recombinant SARS-CoV-2 RBD vaccine candidate produced in yeast, showing high purity, stability, and immunogenicity in mice.

This study identifies cholesterol levels and WBC counts as causal factors for COVID-19 severity through GWAS and MR analysis, and highlights type I interferon pathways in disease mechanisms.