Author

Yunhan Chen

Boston Medical CenterORCID 0000-0002-6891-6715Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Alex OlsoniD· 1 shared Andrés A. Quiñones-MolinaiD· 1 shared Andrew J. HendersoniD· 1 shared Archana AsundiiD· 1 shared Hisashi AkiyamaiD· 1 shared Jacob L. BerriganiD· 1 shared Manish SagariD· 1 shared Sita RamaswamyiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Alex OlsonORCID

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1 paper

Recent·Most cited

Macrophage-intrinsic MDA5-IRF5 axis drives HIV-1 icRNA-induced inflammatory responses

Sita Ramaswamy, Hisashi Akiyama, Jacob L. Berrigan, Andrés A. Quiñones-Molina, Alex Olson, Yunhan Chen, Yan Mei Liang, Andrew J. Henderson, Archana Asundi, Manish Sagar, Suryaram Gummuluru

This study identifies the MDA5-IRF5 axis as critical for HIV-1 icRNA-induced inflammatory responses in macrophages, with IRF5 mediating enhanced IP-10 expression in older individuals.

Journal of Clinical Investigation · Jun 10, 2025Peer-reviewedMicrobiology