Antoine Ghestem

The Internal Structure of Seizures Reflects Animal-Specific Trajectories of Disease Progression and Circadian Modulation in Epileptic Mice

The paper analyzes seizure dynamics in epileptic mice, finding structured, animal-specific trajectories and circadian modulation in seizure microstructure.

Circadian dynamics of the Zbtb14 protein in the ventral hippocampus are disrupted in epileptic mice

This study examines circadian Zbtb14 protein dynamics in the hippocampus of epileptic mice, finding disrupted oscillations and altered gene regulation.

On Global Brain Reconfiguration after Local Manipulations

This study shows how local brain manipulations affect global brain dynamics using simulations and experimental data, revealing specific network changes and localization of effects.

Long-term near-continuous recording with Neuropixels probes in healthy and epileptic rats

This paper introduces a new prosthesis for long-term, near-continuous electrophysiological recordings in rats, achieving high retrieval success rates and improved durability.

Spatio-temporal heterogeneity in hippocampal metabolism in control and epilepsy conditions.

The paper shows that hippocampal metabolism varies along the dorsoventral axis and over time in control mice, with changes in epilepsy affecting this spatio-temporal pattern.

Disordered information processing dynamics in experimental epilepsy

The paper investigates altered information processing dynamics in experimental epilepsy, finding disrupted substate organization during theta and slow oscillations in specific brain regions.

The circadian hippocampus and its reprogramming in epilepsy: impact for chronotherapeutics

The paper identifies daily oscillating transcripts in the hippocampus of control and epileptic mice, showing distinct circadian patterns and implications for drug timing.

Cell assemblies in the cortico-hippocampal-reuniens network during slow oscillations

This study identifies spatially organized neuronal assemblies in the nucleus reuniens during slow oscillations and shows their role in stabilizing prefrontal cortex and hippocampal sequences.

GABA-Glutamate supramammillary neurons control theta and gamma oscillations in the dentate gyrus during paradoxical (REM) sleep

The paper identifies SuML-DG neurons that modulate theta and gamma oscillations in the dentate gyrus during REM sleep and other vigilance states.

Caffeine consumption during pregnancy accelerates the development of cognitive deficits in offspring in a model of tauopathy

The paper shows that early-life caffeine exposure in Tau22 transgenic mice accelerates cognitive deficits linked to Alzheimer's-like pathology.

In vivo characterization of neurophysiological diversity in the lateral supramammillary nucleus during hippocampal sharp-wave ripples of adult rats

The paper analyzes single-cell firing patterns in the lateral supramammillary nucleus during hippocampal sharp-wave ripples in anesthetized rats, identifying differences between neurons active during these events and those that are not.

Effects of single cage housing on stress, cognitive and seizure parameters in the rat and mouse pilocarpine models of epilepsy

This study examines the effects of individual housing on stress, cognitive, and seizure parameters in rat and mouse epilepsy models, finding increased stress and seizures in singly housed animals.