Single cell resolution of an epigenetic signature of persister tumor cell
Mihai Gabriel Dumbrava, Wazim Mohammed Ismail, Letícia Sandoval, Amelia Mazzone, Syed Mohammed Musheer Aalam, Megan L. Ritting, Xiaonan Hou, Yiwen Xie, Shariska Petersen Harrington, Scott H. Kaufmann, Nagarajan Kannan, S. John Weroha, Alexandre Gaspar‐Maia
The paper identifies an epigenetic signature associated with persister tumor cells in ovarian cancer that correlates with chemotherapy resistance and defines the persister state.
bioRxiv · Apr 16, 2025 · PreprintGenomics