Author

Shariska Petersen Harrington

Mayo ClinicORCID 0000-0001-6863-9124Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1 Assay:multiome· 1

Frequent Co-Authors

Alexandre Gaspar‐MaiaiD· 1 shared Amanda J. CompadreiD· 1 shared Amelia MazzoneiD· 1 shared Andrea R. HagemanniD· 1 shared Angela M. SchabiD· 1 shared Ann E. WaltsiD· 1 shared Beth Y. KarlaniD· 1 shared Brooke E. SandersiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Alexandre Gaspar‐MaiaORCID

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2 papers

Recent·Most cited

Replication stress marker phospho-RPA2 predicts response to platinum and PARP inhibitors in homologous recombination-proficient ovarian cancer

Angela M. Schab, Amanda J. Compadre, Rikki Drexler, Megan Loeb, Kevin Rodriguez, Joshua D. Brill, Shariska Petersen Harrington, Carmen Sandoval, Brooke E. Sanders, Lindsay M. Kuroki, Carolyn Kay McCourt, Andrea R. Hagemann, Premal H. Thaker, David Gardner Mutch, Matthew A. Powell, , Mary Margaret Mullen

This study identifies phospho-RPA2 as a biomarker predicting response to platinum and PARP inhibitors in HR-proficient ovarian cancer, showing higher pathologic complete response and longer survival in pRPA2-High tumors.

Journal of Clinical Investigation · May 20, 2025Peer-reviewedCancer Biology

Single cell resolution of an epigenetic signature of persister tumor cell

Mihai Gabriel Dumbrava, Wazim Mohammed Ismail, Letícia Sandoval, Amelia Mazzone, Syed Mohammed Musheer Aalam, Megan L. Ritting, Xiaonan Hou, Yiwen Xie, Shariska Petersen Harrington, Scott H. Kaufmann, Nagarajan Kannan, S. John Weroha, Alexandre Gaspar‐Maia

The paper identifies an epigenetic signature associated with persister tumor cells in ovarian cancer that correlates with chemotherapy resistance and defines the persister state.

bioRxiv · Apr 16, 2025 · PreprintGenomics