MicrobiologybioRxivPreprint
Sequestration of the phagocyte metabolite itaconate by P. aeruginosa RpoN promotes successful pulmonary infection
Ayesha Beg, Zihua Liu, Ying-Tsun Chen…·Alice S. Prince
This study shows that P. aeruginosa sequesters itaconate by binding it to RpoN, enhancing its metabolic adaptation and promoting pulmonary infection.
DOI 10.1101/2025.08.07.669126