Author

Absar Talat

Department of BiotechnologyORCID 0000-0003-0113-3529Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Griffin GowdyiD· 2 shared Ian A. LewisiD· 2 shared Ying-Tsun CheniD· 2 shared Alice Prince· 1 shared Alice S. PrinceiD· 1 shared Asad U. Khan· 1 shared Ayesha Beg· 1 shared Ayesha Zainab BegiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersImmunology

Griffin GowdyORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintMar 19, 2026

T6SS mutants exploit itaconate to support infection of phagocytes

Ayesha Zainab Beg, Blanche L. Fields, Ying-Tsun Chen…·Alice Prince

This study shows that Pseudomonas aeruginosa mutants lacking the H3-T6SS exploit itaconate to persist in phagocytes, enhancing their ability to cause chronic lung infections.

DOI 10.64898/2026.03.11.711069

mousebulk RNA-seq

𝕏 PostBluesky

MicrobiologybioRxivPreprintAug 7, 2025

Sequestration of the phagocyte metabolite itaconate by P. aeruginosa RpoN promotes successful pulmonary infection

Ayesha Beg, Zihua Liu, Ying-Tsun Chen…·Alice S. Prince

This study shows that P. aeruginosa sequesters itaconate by binding it to RpoN, enhancing its metabolic adaptation and promoting pulmonary infection.

DOI 10.1101/2025.08.07.669126

humanproteomics

𝕏 PostBluesky