Jonathan Bradley

The paper introduces a Gateway-based cloning platform for efficient construction of rAAV vectors optimized for neuroscience applications, enabling precise optical interrogation of neural circuits with tools like ULoVE.

This paper introduces VADER1, a red GEVI that enables reliable in vivo two-photon voltage imaging with millisecond resolution and supports dual-color imaging with calcium indicators.

The paper develops two new genetically encoded voltage indicators (JEDI3sub and JEDI3hyp) for improved two-photon recording of subthreshold voltage dynamics in vivo.

The paper introduces FORCE1s, a GEVI that enables robust two-photon voltage imaging in awake mice with high signal-to-noise and reliable spike detection.

The paper introduces a novel rhodopsin-based voltage indicator, 2Photron, enabling simultaneous two-photon recording of spiking and subthreshold voltage with GCaMP in awake mice.

The paper identifies a cerebellar module in the vermis involved in postural anti-gravity maintenance through optogenetic stimulation and movement analysis.

This paper introduces an improved voltage indicator and imaging method to enable high-speed, high-resolution voltage imaging in deeply located neurons of awake mice.