François St-Pierre

This paper identifies NlCCR, a channelrhodopsin from Nutomonas longa, which enables precise optical control of Ca2+ signaling with improved properties compared to existing tools.

This paper introduces VADER1, a red GEVI that enables reliable in vivo two-photon voltage imaging with millisecond resolution and supports dual-color imaging with calcium indicators.

The paper develops two new genetically encoded voltage indicators (JEDI3sub and JEDI3hyp) for improved two-photon recording of subthreshold voltage dynamics in vivo.

The paper introduces FORCE1s, a GEVI that enables robust two-photon voltage imaging in awake mice with high signal-to-noise and reliable spike detection.

The paper introduces MiniFAST, a miniaturized microscope that improves speed, sensitivity, and resolution for in vivo neural recording using genetically encoded indicators.

The paper introduces FACED 2.0, a high-speed imaging technique that enables simultaneous voltage and calcium activity recording in vivo across large neuronal populations.

The paper identifies blue-shifted channelrhodopsins from ancyromonads that enable multiplex optogenetics by conducting chloride or cation currents with improved spectral properties.

This paper develops a brighter and faster voltage indicator, JEDI-1P, enabling single-trial widefield voltage imaging in awake mice.

The paper identifies two distinct synaptic sites on horizontal cells in the mouse retina that mediate local feedback to cones and global feedforward signaling to bipolar cells.

The paper reveals how larval zebrafish retinal circuits process color by rotating spectral information into primary achromatic and chromatic axes at the first synapse, a strategy also used by fruit flies.

This paper introduces an improved voltage indicator and imaging method to enable high-speed, high-resolution voltage imaging in deeply located neurons of awake mice.