Johan Ärnlöv

Marked sex differences and frequent carriage of recognized uropathogens in the human urogenital microbiome: urine profiles from a population-level shotgun metagenomics study

This study characterizes the human urogenital microbiome in a large population cohort, revealing sex-based differences and frequent uropathogen carriage in asymptomatic individuals.

The urinary microbiome in association with diabetes and diabetic kidney disease: A systematic review

This paper reviews studies on the urinary microbiome's association with diabetes and diabetic kidney disease, finding reduced microbial diversity in diabetic individuals and further decline with kidney disease progression.

Genome-wide association analysis reveals insights into the molecular aetiology underlying dilated cardiomyopathy

This study identifies 80 genetic loci and 61 effector genes associated with dilated cardiomyopathy through GWAS and integrates transcriptomic data to uncover biological pathways and cellular states involved in the disease.

Genomic evaluation of circulating proteins for drug target characterisation and precision medicine

The paper identifies pQTLs for cardiovascular proteins and uses them to evaluate drug targets and suggest new candidates for precision medicine.

Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

This study conducts a large GWAS on heart failure, identifying 12 genetic loci with associations to CAD, atrial fibrillation, and reduced left ventricular function, and provides causal evidence for several risk factors.

Trans-ethnic genome-wide association study provides insight into effector genes and molecular mechanisms for kidney function and highlights a causal effect on kidney-specific disease aetiologies

This study identifies 93 genetic loci associated with kidney function across four ancestry groups and highlights causal effects on kidney-related diseases.