Mark R. Buckley

This study shows that voluntary wheel running induces region-specific cellular responses in mouse Achilles tendon that maintain homeostasis by altering collagen fibril size and gene expression.

This study uses 3D imaging to show that aging male mice with osteoarthritis have increased nociceptive nerve remodeling linked to pain, while females show no age-related changes.

This study shows that loss of Cochlin leads to structural and functional impairments in tendons, highlighting its role in maintaining tendon homeostasis.

This study shows exercise increases Piezo1 and Piezo2 in chondrocytes, reducing mechanical susceptibility to impact, with Piezo1 playing a key role in exercise-induced cartilage protection.

This study shows that increased CaV1.2 Ca2+ signaling in tendon fibroblasts leads to tendon hypertrophy, increased collagen fibrillogenesis, and improved biomechanical properties.