Malte Tiburcy

This study shows that geometric confinement and substrate stiffness influence cardiomyocyte force generation differently, with confinement enhancing contractile stress and relaxation on physiological substrates.

This paper presents a correlative imaging platform combining fluorescence microscopy and scanning SAXS to study cellular structures in native conditions, showing agreement between label-free SAXS and labeled fluorescence data.

This study shows that peroxisome dysfunction in mice and engineered human myocardium leads to heart failure through metabolic impairment and disrupted cellular respiration.

SarcAsM provides a multiscale analysis tool for sarcomere structure and dynamics in cardiomyocytes using deep learning and graph-based methods.

This study compares patient-specific stem cell models of RBM20 mutations causing dilated cardiomyopathy and left ventricular non-compaction, identifying distinct molecular, cellular, and functional impairments.