Author

Bryan Charleston

The Pirbright InstituteORCID 0000-0002-6952-9338Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:genome assembly· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Ailish EllisiD· 1 shared Alasdair J. M. HoodiD· 1 shared Alazne R. UnanueiD· 1 shared Antonio Alcamı́iD· 1 shared Bruno HernáeziD· 1 shared Carlos Maluquer de MotesiD· 1 shared Caroline F. WrightiD· 1 shared Carrie BatteniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

Ailish EllisORCID

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2 papers

Recent·Most cited

A high-quality telomere-to-telomere LSDV genome assembly

Caroline F. Wright, Noemi Polo, Sarwar Azam, Graham Freimanis, G. Taru Sharma, Bryan Charleston, Carrie Batten, Tim Downing, Jonas Dutra Albarnaz

The paper presents a high-quality telomere-to-telomere assembly of the LSDV genome using long-read sequencing, resolving structural ambiguities and improving genomic analysis.

bioRxiv · Apr 23, 2026 · PreprintGenomics

Attenuation of the 2022 global outbreak monkeypox virus relative to its clade IIb ancestor

Rebecca P. Sumner, Lucy Eke, Bruno Hernáez, Alasdair J. M. Hood, Telma Sancheira Freitas, Hannah Ashby, Ailish Ellis, Marine J. Petit, Sian Lant, Isobel Stokes, Preetam Parija, I. Alonso, Francisco Javier Alvarez-de Miranda, Alazne R. Unanue, Bryan Charleston, , Carlos Maluquer de Motes

This study compares a 2022 MPXV lineage B.1 virus with its clade IIb ancestor A.1, showing attenuated phenotypes including reduced virulence and immune evasion.

bioRxiv · Feb 27, 2025 · PreprintMicrobiology