Author

Saba Selvi

Gebze Technical UniversityORCID 0000-0002-6965-1384Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Ali Cihan TaşkıniD· 1 shared Alper OkyariD· 1 shared Busra Aytul Akarlar· 1 shared Durişehvar Özer ÜnaliD· 1 shared Fatih AygenliiD· 1 shared İbrahim DANİŞiD· 1 shared İbrahim Halil KavaklıiD· 1 shared Metin TürkayiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Ali Cihan TaşkınORCID

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1 paper

Recent·Most cited

Discovery of a small molecule that selectively destabilizes Cryptochrome 1 and enhances life span in p53 knockout mice

Şeref Gül, Yasemin Kübra Akyel, Zeynep Melis Gül, Safak Isin, Onur Özcan, Tuba Korkmaz, Saba Selvi, İbrahim DANİŞ, Özgecan Şavluğ İpek, Fatih Aygenli, Ali Cihan Taşkın, Busra Aytul Akarlar, Nurhan Özlü, Nuri Öztürk, Narin Öztürk, , İbrahim Halil Kavaklı

The paper identifies a small molecule, M47, that destabilizes CRY1 and extends lifespan in p53 knockout mice by enhancing apoptosis and reducing CRY1 levels.

Nature Communications · Nov 8, 2022Peer-reviewedMolecular Biology