Author

Bart Dermaut

Ghent University HospitalORCID 0000-0002-6968-0572Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexandre PelletieriD· 1 shared Amélie BonnefondiD· 1 shared Ana Raquel Melo de FariasiD· 1 shared Arnaud CarrieriD· 1 shared Benoît FunalotiD· 1 shared Bernard DepypereiD· 1 shared Bruce Graham PoppeiD· 1 shared Bruna Soares LandeiraiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Alexandre PelletierORCID

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2 papers

Recent·Most cited

NeuroscienceActa Neuropathologica CommunicationsPeer-reviewedJan 8, 2022

The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

Erwan Lambert, Orthis Saha, Bruna Soares Landeira…·Pierre Dourlen

This study shows that BIN1 isoform1 causes early endosome defects and neurodegeneration in Drosophila and human neurons, linking it to Alzheimer's disease pathology.

65 citationstop 1%

Drosophilaproteomics

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GeneticsbioRxivPreprintApr 15, 2021

Loss of adipocyte phospholipase gene PLAAT3 causes lipodystrophy and insulin resistance due to inactivated arachidonic acid-mediated PPAR signaling

Nika Schuermans, Salima El Chehadeh, Dimitri Hemelsoet…·Bart Dermaut

The paper identifies PLAAT3 loss-of-function mutations in humans causing lipodystrophy and insulin resistance by impairing arachidonic acid-mediated PPAR signaling in adipose tissue.

1 citation

humanbulk RNA-seq

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