Molecular BiologyPLoS GeneticsPeer-reviewed
Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies
Sangeun Park, Sei-Kyoung Park, Naruaki Watanabe…·Susan Weiss Liebman
The paper shows that CREST toxicity in yeast and flies is reduced by PBP1/ATXN2 deletion, suggesting ATXN2 as a therapeutic target for ALS.
11 citations