Author

Anne-Laure Finoux

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Cell Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Coline ArnouldiD· 4 shared Gaëlle LegubeiD· 4 shared Vincent RocheriD· 4 shared Sarah CollinsiD· 3 shared Raphaël MouradiD· 2 shared Romane Carette· 2 shared Thomas ClouaireiD· 2 shared Aline MarnefiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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4 shared papersMolecular Biology

Coline ArnouldORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Single-cell resolution of resection-dependent chromatin accessibility in response to DNA double-strand breaks reveals specific gene expression programs

Sarah Collins, Anne-Laure Finoux, Coline Arnould, Romane Carette, Vincent Rocher, Gaëlle Legube, Thomas Clouaire

The paper examines chromatin accessibility changes at DNA double-strand breaks (DSBs) in single cells, revealing resection-dependent remodeling and associated gene expression programs.

bioRxiv · Apr 23, 2026 · PreprintCell Biology

Circadian PERIOD proteins regulate TC-DSB repair through anchoring to the nuclear envelope

Benjamin Le Bozec, Laure Guitton-Sert, Sarah Collins, Anne-Laure Finoux, Charlotte Payrault, Emmanuelle Guillou, Marion Aguirrebengoa, Vanessa Dougados, Virginie Jouffret, Jessica Frison, Romane Carette, Vincent Rocher, Coline Arnould, Aude Guénolé, Ikrame Lazar, , Gaëlle Legube

The paper identifies PERIOD proteins as regulators of TC-DSB repair by anchoring DSBs to the nuclear envelope, linking circadian rhythms to DNA repair mechanisms.

Molecular Cell · Nov 20, 2025Peer-reviewedMolecular Biology

A novel class of non-coding variants driving DNA double-strand breaks is associated with complex genetic diseases

Sébastien Auber, Sarah Collins, Andrey Buyan, Ariuna Z Aiusheeva, Anne-Laure Finoux, Florian Saur, Sarah Cohen, Vincent Rocher, Coline Arnould, Marie Verbanck, Ivan V. Kulakovskiy, Gaëlle Legube, Raphaël Mourad

The paper identifies a new class of non-coding variants, dsbSNPs, that modulate DNA double-strand break frequency and are enriched in GWAS associations for complex diseases.

medRxiv · Oct 16, 2025 · PreprintGenetic & Genomic Medicine

Loop extrusion as a mechanism for DNA Double-Strand Breaks repair foci formation

Coline Arnould, Vincent Rocher, Anne-Laure Finoux, Thomas Clouaire, Kevin Li, Felix Y. Zhou, Pierre Caron, Philippe. E. Mangeot, Emiliano P. Ricci, Raphaël Mourad, James E. Haber, Daan Noordermeer, Gaëlle Legube

The paper identifies TADs as functional units in DDR, showing cohesin-mediated loop extrusion contributes to {gamma}H2AX/53BP1 domain formation during DSB repair.

Nature · Feb 17, 2021Peer-reviewedMolecular Biology