Nicola Elvassore

This study shows that human fibroblasts can be converted into neurons via NGN2 overexpression after partial reprogramming for 3 days, identifying intermediate cell states that influence conversion efficiency.

The paper develops multi-regional gastric assembloids from patient-derived organoids to model parietal cell maturation and antral foveolar hyperplasia in genetic disorders.

The paper develops a 3D in vitro model of graft-host skeletal muscle interaction using decellularized skeletal muscle constructs and neuromuscular organoids, showing functional neuromuscular junction formation and regeneration.

This paper investigates VEGF supplementation as a treatment for congenital diaphragmatic hernia (CDH)-associated lung abnormalities using an ex vivo model and nanoparticle-based delivery in vivo.

This paper develops a 3D model of human CNS development from naive hiPSCs, showing their ability to form neuroepithelial cysts and model FXS with epigenetic changes.

The paper shows how floorplate organiser forms autonomously in neural tube organoids through BMP-mediated cluster competition and FOXA2 dynamics.