Author

Xiaoping Fan

Guangdong Academy of Medical SciencesORCID 0000-0002-7067-7450Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Autumn R. DeHartiD· 1 shared Dunpeng CaiiD· 1 shared Feng LiuiD· 1 shared Gretel Toloza‐AlvareziD· 1 shared Hong YueiD· 1 shared Huanlei HuangiD· 1 shared Jian ZhuangiD· 1 shared Jiawei Hao· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Autumn R. DeHartORCID

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2 papers

Recent·Most cited

Genetic analyses identify shared genetic components related to autoimmune and cardiovascular diseases

Jun Qiao, Minjing Chang, Miaoran Chen, Yuhui Zhao, Jiawei Hao, Pengwei Zhang, Ruixin Zhou, Liuyang Cai, Feng Liu, Xiaoping Fan, Siim Pauklin, Rongjun Zou, Zhixiu Li, Yuliang Feng

This study identifies shared genetic components between autoimmune and cardiovascular diseases through genome-wide pleiotropy analyses and functional annotations.

medRxiv · Sep 1, 2024 · PreprintGenetic & Genomic Medicine

Thymidine Phosphorylase Promotes the Formation of Abdominal Aortic Aneurysm in Mice Fed a Western Diet

Liang Hong, Hong Yue, Dunpeng Cai, Autumn R. DeHart, Gretel Toloza‐Alvarez, Lili Du, Xianwu Zhou, Xiaoping Fan, Huanlei Huang, Shi‐You Chen, Shaik O. Rahaman, Jian Zhuang, Wei Li

This study shows that TYMP promotes abdominal aortic aneurysm (AAA) in mice fed a Western diet by enhancing inflammation, thrombosis, and MMP2 activation while inhibiting vascular smooth muscle cell function.

Cardiovascular Therapeutics · Jan 1, 2024Peer-reviewedCell Biology