Synthetic BiologybioRxivPreprint
Fine tuning of CpG spatial distribution with DNA origami for improved therapeutic cancer vaccination
Yang C. Zeng, Olivia J. Young, Christopher M. Wintersinger…·William M. Shih
This study developed a DNA origami-based cancer vaccine that co-delivers antigen and CpG immune adjuvant with an optimal nanospacing for Th1 immune polarization.
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