Kenta Yamauchi

The paper reconstructs growth cones of callosal projection neurons in the developing mouse brain and finds they have a planar, dorsoventrally oriented morphology with filopodia that precede accelerated axon growth.

The paper evaluates the immunohistochemical reactivity of three anti-Aβ antibodies in AD mouse models, finding significant differences in staining patterns and suggesting antibody-specific effects beyond sensitivity.

This paper introduces a 3D immunolabeling method for high-speed and high-sensitive detection of targets in 3D tissues, demonstrating its application in visualizing neuronal and glial cells in mouse brain tissues.

The paper identifies plaque-associated endogenous IgG in AD mouse models that interferes with immunohistochemical detection of mouse monoclonal IgG antibodies and shows that subclass-specific secondary antibodies can mitigate this issue.

FT-GO improves fluorescent histochemical analysis by enhancing signal detection while reducing background noise in mouse and marmoset brains.

This paper develops a multi-scale neuronal imaging technique combining light and electron microscopy with a tissue clearing method to study brain-wide connectivity across multiple spatial scales.