Shogo Ito

The difference in immunohistochemical reactivity of monoclonal antibodies against amino-terminal residues of amyloid-β peptide

The paper evaluates the immunohistochemical reactivity of three anti-Aβ antibodies in AD mouse models, finding significant differences in staining patterns and suggesting antibody-specific effects beyond sensitivity.

A CRISPR/Cas9-induced restoration of bioluminescence reporter system for single-cell gene expression analysis in plants

The paper develops CiRBS, a CRISPR/Cas9-induced restoration system for single-cell bioluminescence monitoring in Arabidopsis to analyze gene expression heterogeneity and temporal fluctuations.

Quantitative manipulation of the photoperiodic flowering by a small-molecule clock modulator

The paper shows how a small-molecule clock modulator can quantitatively alter the critical day length required for flowering in monocots.

Companion cells with high florigen production express other small proteins and reveal a nitrogen-sensitive FT repressor

The paper identifies FT-expressing companion cells in leaves, reveals their unique gene expression profile, and shows that NIGT1 represses FT under nitrogen-rich conditions.

Model-based analysis of the circadian rhythm generation of bioluminescence reporter activity in duckweed

This study uses model-based analysis to determine that luminescence efficiency, not luciferase stability, drives circadian bioluminescence rhythms in duckweed.

Florigen-producing cells express FPF1-LIKE PROTEIN 1 that accelerates flowering and stem growth in long days with sunlight red/far-red ratio in Arabidopsis

The paper identifies FLP1 as a gene expressed in FT-producing cells in Arabidopsis that promotes flowering and stem growth under long-day conditions.

Plaque-associated endogenous IgG and its impact on immunohistochemical detection of mouse monoclonal IgG antibodies in mouse models of Alzheimer's disease

The paper identifies plaque-associated endogenous IgG in AD mouse models that interferes with immunohistochemical detection of mouse monoclonal IgG antibodies and shows that subclass-specific secondary antibodies can mitigate this issue.