Author

Angelo Demuro

University of California, IrvineORCID 0000-0002-7112-1681Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 2 Research Focus:software / tool· 2 Approach:statistical model· 2 Assay:electronic health records· 1 Approach:experimental assay· 1

Frequent Co-Authors

Ghanim UllahiD· 3 shared Syed Islamuddin ShahiD· 3 shared Ian ParkeriD· 2 shared David A. RabsoniD· 1 shared Divya SwaminathaniD· 1 shared Don‐On Daniel MakiD· 1 shared John E. PearsoniD· 1 shared Martin Smith· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 22 mutual co-author links

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3 shared papersBioinformatics

Ghanim UllahORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintApr 21, 2022

Upregulated Ca2+ release from the endoplasmic reticulum leads to impaired presynaptic function in Alzheimer's disease

Temitope Adeoye, Syed Islamuddin Shah, Angelo Demuro…·Ghanim Ullah

This study uses a biophysical model of hippocampal synapses to show that enhanced ER Ca2+ release in Alzheimer's disease increases neurotransmitter release probability and short-term plasticity, while causing depression and desynchronization during prolonged stimulation.

5 citations

statistical model

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BioinformaticsBiophysical JournalPeer-reviewedOct 25, 2018

CellSpecks: A Software for Automated Detection and Analysis of Calcium Channels in Live Cells

Syed Islamuddin Shah, Martin Smith, Divya Swaminathan…·Angelo Demuro

CellSpecks automates the detection and analysis of ion channel activity in live cells, providing detailed kinetic data from high-throughput imaging experiments.

5 citations

imagingexperimental assay

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BioinformaticsBiophysical JournalPeer-reviewedJul 1, 2018

TraceSpecks: a software for automated idealization of noisy patch-clamp and imaging data

Syed Islamuddin Shah, Angelo Demuro, Don‐On Daniel Mak…·Ghanim Ullah

TraceSpecks automates noise removal and state quantification in patch-clamp and imaging data, providing accurate and detailed analysis of ion channel behavior.

13 citations

imagingelectronic health records

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