Syed Islamuddin Shah

ProtPipe is a data analysis pipeline for proteomics and peptidomics that automates processing, quality control, and downstream analysis of mass spectrometry data.

DL-SCAN automates cell segmentation and analysis in fluorescence microscopy images, improving consistency and reducing user bias in ion dynamics studies.

The paper shows that loss of TDP-43 function leads to the expression of de novo proteins from mis-spliced mRNA transcripts in ALS/FTD.

The paper identifies gene co-expression modules driving pathway dysregulation in Alzheimer's disease using single-nucleus RNA-seq data from brain regions.

This study uses a biophysical model of hippocampal synapses to show that enhanced ER Ca2+ release in Alzheimer's disease increases neurotransmitter release probability and short-term plasticity, while causing depression and desynchronization during prolonged stimulation.

CellSpecks automates the detection and analysis of ion channel activity in live cells, providing detailed kinetic data from high-throughput imaging experiments.

TraceSpecks automates noise removal and state quantification in patch-clamp and imaging data, providing accurate and detailed analysis of ion channel behavior.